Keyto's bonded manifold is made by molecular bonding of multi-layer processed parts with specific flow path features and supports up to five layers. It integrates functions such as sample addition, dilution, reagent mixing, reaction, separation, and detection, saving reagents and enhancing system integration. The manifold supports multi-level, multi-fluid path designs with material options including PMMA, PEI, and PVC, and offers O-type, square, and D-type flow path structures. Keyto's O-type structure provides large fluidity, low resistance, and minimal dead volume, supported by mature mass production capabilities.